Researchers Create Scoring System for PTEN Mutation Testing

Led by Dr Charis Eng,  the study established more stringent diagnostic criteria as to who should undergo testing for PTEN mutation.  In addition, the study established that a higher diagnostic store correlates with lower PTEN proteins.  “ A higher diagnostic score correlates with lower PTEN protein, substantiating previous laboratory studies that show lower PTEN levels associate with carcinogenesis. ‘This is the first human evidence of a causal relationship between PTEN protein deficiency and disease manifestation, which had only been previously been shown in the laboratory dish or animal model,’ Eng remarked.”

http://www.sciencedaily.com/releases/2011/01/110110103828.htm

May 1, 2011 · PTENLife · No Comments
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