New York Times Article “Autism’s Unexpected Link to Cancer” and reactions to the article from Forbes “Dear New York Times: Cancer and Autism are Not Parallels” and Autism Speaks “Confusing Newspaper Article Implies Link Between Autism and Cancer”

The New York Times article:

http://www.nytimes.com/2013/08/13/health/autisms-unexpected-link-to-cancer-gene.html?pagewanted=all&_r=0

Reaction from Forbes:

http://www.forbes.com/sites/emilywillingham/2013/08/11/autism-and-cancer-are-not-parallels/

Reaction from Autism Speaks:

http://www.autismspeaks.org/science/science-news/confusing-newspaper-article-implies-link-between-autism-and-cancer

 

 

August 18, 2013 · Lucy · No Comments
Posted in: PTEN Life

Dutch website providing support to people with a PTEN mutation

Myrna Zandvoort-Zee and other volunteers have launched a website to support families and people with a PTEN mutation living in Holland and Belgium.

http://pten.nl

Several Dutch PTEN specialists have assisted Myrna in providing the site with insightful content.   Although written in Dutch, non-Dutch readers can view the content by using one of the translate tools available with Internet Explorer or Google Chrome translate.

 

December 1, 2012 · PTENLife · No Comments
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Article on Proposed Changes to the Definition of Autism

http://www.nytimes.com/2012/01/20/health/research/new-autism-definition-would-exclude-many-study-suggests.html?pagewanted=all

February 6, 2012 · PTENLife · No Comments
Tags:  · Posted in: Autism

Hacking Autism – An initiative to develop high-tech tablets and applications for communication

http://www.hackingautism.org/

February 6, 2012 · PTENLife · No Comments
Tags: ,  · Posted in: Autism, Treatment

Lifetime Cancer Risks in Individuals with Germline PTEN Mutations – NEW SCREENING RECOMMENDATIONS

SEE TABLE 4 WITH NEW SCREENING RECOMMENDATIONS

 

February 6, 2012 · PTENLife · 6 Comments
Tags: , ,  · Posted in: Medical, PTEN Mutation, Screening

Mutation in PTEN Gene Can Cause Cancer and Autoimmune disease

http://www.sciencedaily.com/releases/1999/09/990927065349.htm

December 9, 2011 · PTENLife · One Comment
Tags: ,  · Posted in: Cancer, PTEN Mutation

PTEN Hamartoma Tumor Syndrome by Dr Charis Eng

http://www.ncbi.nlm.nih.gov/books/NBK1488/

November 11, 2011 · PTENLife · No Comments
Tags: , , ,  · Posted in: Cancer, PTEN Mutation

A Mutant Form of PTEN Linked to Autism

http://www.ncbi.nlm.nih.gov/pubmed/20718038

November 11, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, Causes, PTEN Mutation

Rat Study Ties Antidepressants to Autism Like Brain Abnormalities

http://psychcentral.com/news/2011/10/26/rat-study-ties-antidepressants-to-autism-like-brain-abnormalities/30761.html

November 11, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, Causes

Autism Linked to Unusual Shape in Lungs

http://www.webmd.com/brain/autism/news/20111025/autism-linked-to-unusual-airway-shapes

November 11, 2011 · PTENLife · No Comments
Tags: ,  · Posted in: Autism, Medical, Respiratory Issues

NY Becomes 29th State to Adopt Autism Insurance Reform – From the Autism Speaks Blog

http://feedproxy.google.com/~r/AutismSpeaksBlog/~3/MDKRy9FW-zo/

November 11, 2011 · PTENLife · No Comments
Tags: ,  · Posted in: Autism, Medical

California Autism Twin Study Suggests Prenatal Risk Factors

http://www.autismspeaks.org/science/science-news/womb-environment

July 19, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, Causes, Medical

Curemark Completes Enrollment of Phase III Autism Trial

http://www.curemark.com/news/2011/03/21/curemark-completes-enrollment-of-phase-iii-autism-trials/

http://www.curemark.com/disease-targets/autism/

May 8, 2011 · PTENLife · No Comments
Tags: ,  · Posted in: Autism, Treatment

The Power of a Teacher

Tommy and his swim coach:

http://www.ryerecord.com/Rye%20Record%20Website%2005.06.11/Big%20Strokes.htm

May 8, 2011 · PTENLife · 3 Comments
Tags: ,  · Posted in: Autism, Treatment

Simple Quiz Speeds Diagnosis of Autism in Infants

http://online.wsj.com/article/SB10001424052748703367004576289360947431574.html?mod=djemalertNEWS

May 1, 2011 · PTENLife · 2 Comments
Tags: , ,  · Posted in: Autism, PTEN Life, Screening

Benign Growths and Lesions

Dr Eng mentioned that in general certain benign growths and lesions should not be removed in patients with a PTEN mutation as they tend to regrow even larger (examples were lesions of the mouth, face and hands that have not been seen to become malignant).  Of course, these should be checked and followed by a doctor.  She was pleased that Tommy had a full tonsillectomy because if any tonsil tissue had been left behind (as would be the case with a partial tonsillectomy), the chances of regrowth were far greater.  She also mentioned that if Tommy’s thyroid ever needs to be removed for a malignancy, it should be removed in full as they have not had much success with partial removals (the thyroid regrows with the malignancy).  Because thyroid problems are so common in patients with a PTEN mutation, we had a baseline sonogram done of Tommy’s thyroid.  Regular thyroid sonograms are recommended beginning at age 18 for patients with a PTEN mutation (there are other additional screening guidelines for patients with a PTEN mutation).  Finally, she explained to us that she has a theory that patients with a PTEN mutation metabolize medicine faster than the average population.  Tommy is participating in two studies being conducted by Dr Eng.

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Growths and Lesions, Medical, PTEN Life, PTEN Mutation

Dural Arteriovenous Malformation in a Child with BRRS

http://www.ajnr.org/cgi/reprint/27/9/1927.pdf

May 1, 2011 · PTENLife · No Comments
Tags: , , ,  · Posted in: Arteriovenous Malformations, Medical, PTEN Life, PTEN Mutation

Lhermitte Duclos Disease and Multiple Hamartoma Syndrome

Lhermitte Duclos Disease is a rare tumor of the cerebellum that grows slowly.

http://www.associatedcontent.com/article/2774918/lhermitteduclos_disease_pg2.html?cat=5

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Growths and Lesions, Medical, PTEN Life, PTEN Mutation

MIT Research: Multiple Genes Implicated in Autism in Mice

Massachusetts Institute of Technology looked at how mutations in PTEN and serotonin transporter genes together produce greater autism symptoms in mice.

http://web.mit.edu/newsoffice/2009/autism-gene-0209.html

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, PTEN Life, PTEN Mutation

Mutation of the KILLIN gene is responsible for Cowden like symptoms in people without PTEN mutation

http://www.cleveland.com/medical/index.ssf/2010/12/cleveland_clinic_researchers_h.html

May 1, 2011 · PTENLife · No Comments
Tags: ,  · Posted in: Growths and Lesions, Medical, PTEN Life

Researchers Create Scoring System for PTEN Mutation Testing

Led by Dr Charis Eng,  the study established more stringent diagnostic criteria as to who should undergo testing for PTEN mutation.  In addition, the study established that a higher diagnostic store correlates with lower PTEN proteins.  “ A higher diagnostic score correlates with lower PTEN protein, substantiating previous laboratory studies that show lower PTEN levels associate with carcinogenesis. ‘This is the first human evidence of a causal relationship between PTEN protein deficiency and disease manifestation, which had only been previously been shown in the laboratory dish or animal model,’ Eng remarked.”

http://www.sciencedaily.com/releases/2011/01/110110103828.htm

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Medical, PTEN Life, PTEN Mutation, Screening

Seaside Therapeutics is creating a new Autism drug treatment

Seaside Therapeutics Reports Positive Data from Phase 2 Study of STX209 in Autism Spectrum Disorders.  Study to Advance.

http://www.seasidetherapeutics.com/sites/default/files/news_media-release_2010-09-09.pdf

And reports advances in the treatment of Fragile X Syndrome.

http://www.seasidetherapeutics.com/sites/default/files/Seaside_ACS_release_5_18_2011.pdf

They have a pipeline summary of the drugs they are investigating for treatment of Autism and Fragile X.

http://www.seasidetherapeutics.com/pipeline-overview

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, PTEN Life, Treatment

Should Autistic Children be tested for the PTEN Mutation

http://www.associatedcontent.com/article/2991138/should_autistic_children_be_tested_pg2.html?cat=25

May 1, 2011 · PTENLife · No Comments
Tags: , , ,  · Posted in: Autism, PTEN Life, PTEN Mutation, Screening

The Dr Oz Show addresses the controversial topic of what causes autism

http://www.doctoroz.com/videos/what-causes-autism-pt-1?hs317=billboard_5

May 1, 2011 · PTENLife · No Comments
Tags: , ,  · Posted in: Autism, Causes, PTEN Life

The Genetics of PTEN Mutations, Symptoms, Diagnosis and Cancer Screening Protocols

Information including, what is a PTEN mutation, what are the clinical symptoms, how is it diagnosed, how is it inherited, reproductive options for people with the mutation wishing not to pass it on, and cancer screening protocols.

http://www.chop.edu/service/hereditary-cancer-predisposition-program/genetic-syndromes-with-cancer-risks/pten-hamartoma-tumor-syndrome.html

May 1, 2011 · PTENLife · No Comments
Tags: , , , , ,  · Posted in: Autism, Macrocephaly, Medical, PTEN Life, PTEN Mutation, Screening